Flights from Mexico City (MEX) to Santiago (SCL)

Route intelligence for MEX → SCL: direct flights, stopover options, and timetable coverage in one place.

Show route on mapAll flights from MEXAll flights to SCL

Direct flights

2 direct option(s) across 2 airline(s) · 6,596 km route distance.

  • AeroMéxico · 532 min · 6596 km
  • LATAM Airlines · 532 min · 6596 km

Explore these airlines on this city pair

Open each airline route-map page to compare broader network depth before committing to a nonstop or one-stop strategy.

AeroMéxico route map →LATAM Airlines route map →

Stopover options

  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL
  • 1 stop(s) · 11h 41m · MEX → SCL

Timetable coverage

Published flight numbers: LA621

Flight number: LA 621

Operating days: 1, 2, 3, 4, 5, 6, 7

  • MEX 20:20 → SCL 06:20

Plan this city pair

Compare nearby alternatives and airline networks to decide whether a direct trip, one-stop connection, or reverse search gives you better options.

Explore all departures from MEX →Explore all arrivals to SCL →Compare airline network coverage →Browse airports by country →

Route planning checklist

  • Compare direct duration with one-stop total duration before committing to a fare.
  • Check inbound alternatives on flights to SCL when return timing is important.
  • Use Guides for alliance and hub strategy playbooks.
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